How will AI transform business in 2026?

How should leaders prepare for AI ’s accelerating impact on work and everyday life? AI scientist, entrepreneur, and Pioneers of AI podcast host Rana el Kaliouby shares her predictions for the year ahead—from physical AI entering the real world to what it means to onboard AI into your org chart. El Kaliouby cuts through today’s biggest AI headlines, bringing to light the insights that will matter most in the months to come. This is an abridged transcript of an interview from Rapid Response , hosted by former Fast Company editor-in-chief Robert Safian. From the team behind the Masters of Scale podcast, Rapid Response features candid conversations with today’s top business leaders navigating real-time challenges. Subscribe to Rapid Response wherever you get your podcasts to ensure you never miss an episode. Let’s look ahead to 2026. You sent me some fascinating thoughts about AI’s next-phase impact on business, and I’d love to take you through them. The first one was the rise of what you called relationship intelligent AI. So everybody’s worried that AI is going to make us less human and take away our human-to-human connections. There is definitely a risk of that. But I think the thing I’m most excited about for 2026 is how AI can actually help us build deeper human connections and more meaningful human experiences. And the way this happens is through AI that can really help you organize your relationships and your network and surface connections that you need and maybe make warm introductions to you. I love connecting with people, but my relationship data is a mess. It’s all in my brain. Some of it is in LinkedIn, some are on WhatsApp. I take a lot of notes when I meet new people and I use an AI note taker. It’s just a mess. It’s very disparate data sources. And I always think of this scene in, do you know The Devil Wears Prada ? Have you seen? Oh, that’s exactly what I was thinking of. The character is kind of whispering in your ear. Exactly. It was Anne Hathaway [as Andy], and she was with Meryl Streep [as Miranda] at this gala. And this guy and his partner were moving toward Miranda and she [didn’t rememeber their names]. And Andy whispers in Miranda’s ear: “He’s the ambassador and his new wife.” And I was like, “That’s exactly what I need. I need an AI version of Anne Hathaway.” And it’s now doable with LLMs because it’s all this unstructured, messy data that an AI can take all of that, contextualize it, and hopefully be that AI chief of staff for you. Is that like a product? Is that something that you would have to do to turn your chatbot, whatever, your Claude or your ChatGPT into that? Or is it a new product that you think is going to come out that will make that easy for you? There are already a number of new companies that are starting in this space....

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